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Chronic Granulomatous Disease (CGD)

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Chronic Granulomatous Disease (CGD)

Chronic Granulomatous Disease (CGD)

(CGD) Chronic Granulomatous Disease is an inherited disorder, which fails to destroy bacteria and fungi and highly affects neutrophils and phagocytes.

Symptoms

CGD shows many kinds of symptoms starting from minor ones to the ones which are long-lasting:

  • Swollen Lymph glands
  • Bone Infection
  • Skin rashes
  • Pneumonia
  • Diarrhea
  • Fever
  • Chest Pain

Causes

As it is a genetic disorder, when parents pass the gene mutation to the upcoming generation, mutations like NCF1, NCF2 and NCF4 generally cause CGD and at some point CYBA and CYBB can also be responsible for such conditions

More about Treatment

Commonly known as primary immunodeficiency, Chronic Granulomatous Disease is an inherited disease, it usually occurs when the capacity of WBC (White Blood Cells) to form oxygen activated compounds, decreases and weakens phagocytic cells, as a result infection spreads.

This infection starts spreading from skin and also passes through the internal organs such as lungs, liver, stomach, spleen and may happen in other body parts.  In the early stage of the life, Chronic Granulomatous Disease doesn’t affect the body but when the child grows the chances to develop infection increases. In many cases, the problem becomes so intense that, to admit in the hospital becomes the only life-savior option.

The good thing is Chronic Granulomatous Disease is not common; only 5-7 people in a million get affected by this. Men get affected more than women, the reason is CGD is inherited in an X-linked pattern.

CHRONIC GRANULOMATOUS DISEASE TREATMENT

To nullify the chances of infection, preventive antibiotics and some precautions can definitely come to the rescue: 

  • To cure the inflamed tissues corticosteroids can be effective.
  • The major thing which one should include is antifungal medicines.
  • To avoid the unnecessary risks bone marrow transplant can be done.
  • Interferon- gamma injections can protect from infections.
  • Stem cell transplant is a very useful and efficient method but it requires a matchable donor.
  • Granulocyte transfusion also holds a great promise as a future cure.

FAQ

1. How is Chronic Granulomatous Disease diagnosed?

Doctors diagnose on the basis of its intensity level and symptoms some tests like nitro blue tetrazolium test, some common genetic tests and respiratory burst assay are among the popular tests.

2. Which type of doctor should be preferred for CGD treatment?

General surgeon or Pathologist for biopsy and for check-ups general physician and hematologist should be preferred.

3. Is it possible to vanish CGD?

Yes, if the WBCs become more active along with immune cells then it is possible.

4. Does CGD cause blockage?

Yes, in some areas it does such as in the urinary tract, in the brain and even in the intestinal tract.

5. What is the Chronic Granulomatous Disease’s life expectancy?

Nowadays due to several test facilities and with the options of numerous antibiotics and therapies people can live up to 45-50 years.

6. What to avoid in Chronic Granulomatous Disease?

Swimming

Stop smoking Marijuana

Avoid to sit in park’s hayrides

Sanitizing cellars

Top Doctors For Chronic Granulomatous Disease (CGD) Treatment

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Dr. Ranjan Kumar Mohapatra Bone Marrow Transplant (BMT) | Gender: Male | Experience: 25 years | Hospital: SIMS Hospital, Chennai
Ms. Aruna Mallya Bariatric – Weight Reduction | Gender: Female | Experience: 10 years | Hospital: Manipal Hospitals, Bengaluru
Ms. Bhakti Samant Bariatric – Weight Reduction | Gender: Female | Experience: 12 years | Hospital: Kokilaben Dhirubhai Ambani Hospital
Dr. Garud Chandan Family Medicine | Gender: Male | Experience: 17 years | Hospital: Fortis Hospital, Bengaluru
Dr. Anita Kaul Emergency Medicine | Gender: Female | Experience: 25 years | Hospital: Apollo Indraprastha
Dr. Mehmet Yılmaz Eltemmo Bone Marrow Transplant (BMT) | Gender: Male | Experience: 10 years | Hospital: Hisar Intercontinental
Dr. (Col.) Kumud Rai Cardiovascular | Gender: Male | Experience: 25 years | Hospital: Max Super Speciality Hospital, Saket
Dr. Yogesh Gautam Bariatric – Weight Reduction | Gender: Male | Experience: 10 years | Hospital: Max Super Speciality Hospital, Saket
Ms. Hiba Khalid Dietician | Gender: Female | Experience: 7 years | Hospital: RAK Hospital
Dr. Arun Kumar Goyal Cardiovascular | Gender: Male | Experience: 25 years | Hospital: RAK Hospital
Dr. Humam Sami Ali Family Medicine | Gender: Male | Experience: 25 years | Hospital: RAK Hospital
Dr. Kavuri Sree R. Murthy Family Medicine | Gender: Male | Experience: 22 years | Hospital: RAK Hospital
Dr. Fatima Attiya Al Hussain Emergency Medicine | Gender: Female | Experience: 10 years | Hospital: RAK Hospital
Dr. Nidal Mohamed Eldahla Family Medicine | Gender: Male | Experience: 30 years | Hospital: RAK Hospital
Ms. Ruba Elhourani Dietician | Gender: Female | Experience: 5 years | Hospital: RAK Hospital
Dr. Abhay Nigam Family Medicine | Gender: Male | Experience: 32 years | Hospital: RAK Hospital
Dr. Tope Titilayo Odofafa Emergency Medicine | Gender: Female | Experience: 10 years | Hospital: RAK Hospital
Dr. Elhadi Eltayeb Abbas Family Medicine | Gender: Male | Experience: 32 years | Hospital: RAK Hospital
Dr. Issam Hreirati Bariatric – Weight Reduction | Gender: Male | Experience: 25 years | Hospital: Saudi German Hospital
Dr. Sameer Sudhakar Diwale Cardiovascular | Gender: Male | Experience: 23 years | Hospital: Saudi German Hospital
Dr. Abha Gupta Allergy and Immunology | Gender: Female | Experience: 31 years | Hospital: Apollo Indraprastha

Top Hospitals For Chronic Granulomatous Disease (CGD) Treatment

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Fortis Malar Hospital, Chennai Fortis Malar Hospital, Chennai is a leading multi-specialty, tertiary care hospital which offers com
Manipal Hospitals, Bengaluru Manipal Hospitals is one of India's foremost multi-specialty healthcare providers catering to both I
Narayana Hospital At Narayana Health, 'quality' and 'lowest cost' are not mutually exclusive when it comes to healthca
Apollo Indraprastha Indraprastha Apollo Hospitals, New Delhi is the First Hospital in India to be Internationally Accred
BLK Hospitals BLK Super Specialty Hospitals, New Delhi, has a unique combination of the best in class technology,
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